Kanna vs Kratom: The Ultimate Showdown

Kanna vs Kratom

Many state that they take kratom for anxiety and pain relief. It’s believed that this is due to the alkaloids present in kratom. If you’re someone who isn’t sure about Kanna vs kratom, then you might wonder about the differences between them. This article is the ultimate showdown between the two to explore the similarities and differences. Read on to explore more about these 2 herbs in order to decide which is right for you. 

What Is Kratom? 

Kratom comes from a tropical evergreen tree that grows in Southeast Asia. It’s native to Papua New Guinea, Indonesia, Thailand, and Malaysia.

It’s a member of the Rubiaceae family. Other members of this family include gardenia and coffee. 

In the past, workers and natives would use it to limit fatigue, increase energy, and stamina. Today, many in the U.S. claim that it helps with the relief of pain, diarrhea, and other symptoms. 

Kratom Alkaloids

There are more than 20 alkaloids found in kratom. Many believe that Mitragynine, the kappa-opioid receptor is responsible for the opioid-like effects. 

Mitragynine occurs at the mu and delta-opioid receptors. It can also be at the noradrenergic and serotonergic pathways in the spinal cord. You might also find stimulation at post-synaptic alpha-2 adrenergic receptors. 

Kratom Effects

One study finds that kratom can be used as a harm reduction tool. They find it can be used as a substitute for opioids for those who have an addiction. It’s found to also relieve anxiety, and enhance your mood. 

Another study finds that Mitragynine has analgesic and opioid agonist qualities. It’s also found that it can limit the negative side effects of typical opioids. 

A Kratom Dosage Guide

If you’re just starting out with kratom, you’ll want to start small. Take a gram, and see how you feel after about 30 minutes.

If you don’t feel anything, take a bit more and wait. Avoid taking large doses. 

It’s about identifying the lowest amount you need in order to feel the effects. Once you know that dose, you can write it down and reference it again in the future.

Keep in mind that each strain will have different levels of potency. Each brand might have varying effects as well.

Keep a log with how much kratom you take, the type, and what effects you feel.

Make sure that you stay hydrated before, during, and after taking kratom. This is because it can dehydrate you (similar to coffee and tea). 

In order to have the best chance of feeling the effects, take it on an empty stomach. Never mix it with alcohol.

If you’re currently on medication or have a medical condition, speak with your doctor first. As with other medications, it can have interactions with certain drugs. 

Kratom’s side effects can include nausea, especially if you overdose. High doses can lead to constipation, nervousness, and darkening of the skin. 

How To Take Kratom? 

From capsules to powder, you have options when it comes to kratom. Determine whether or not you like the flavor in order to help you decide which method is best for you.


This is the best method for a discreet option. It’s also one of the easiest since you can take it anywhere. For those who don’t like the taste of kratom, this is a good way to avoid the flavor. 


You can place kratom in your favorite smoothies. First, pour your favorite milk (or milk alternative) into a blender, fruit, spinach, and kratom powder. Blend it up and then enjoy.

Toss and Wash

Another option is the toss and wash method. First, measure out the dose of kratom you’ll be taking. 

Next, take a portion of that kratom and place it on your tongue. Rinse it down with your favorite juice of choice. Repeat until the kratom is complete. 


First, you’ll need a strainer, kratom powder, water, and a kettle. Use about 1 1/2 cups of water in a kettle. Bring it to a soft boil. 

Place the amount of kratom you’d like to take into the simmering water. Lower the heat and let the kratom mix with the water for 10 minutes. 

Once it’s about a deep orange or yellow color, you can remove it. Use a strainer over your mug in order to pour the liquid through. 

You can save the leftover powder for future use or dispose of it. In order to flavor it, you can use cinnamon, sugar, or honey. Place a slice of lemon in order to ensure that the alkaloids stay. 

What Is Kanna? 

Another term for Kanna is known as the Sceletium Toruosum. It’s a part of the Aizoaceae family that’s from South Africa. 

The San and Khoikhoi people of South Africa have used it for centuries. In the past, you can find chewing or smoking during social events or ceremonies.

Similar to kratom, it has many different alkaloids as well. The main alkaloids are Mesembrenone and Mesembrine. You can find it around the world and easier to find than kratom. 

Many claim that Kanna effects include stimulation at lower doses and intense relaxation at higher doses. It’s known to be an appetite suppressant as well. 

A Kanna Dosage Guide

If you decide to take Kanna through oral ingestion, the dosage can vary between 500-2000 mg. Keep in mind that when you’re first beginning, you’ll want to start out small and see what amount works best for you.

If you’re taking capsules, you’ll want to take 1-2 daily. Take 10 drops of tinctures. For tea, you’ll want to take about 1-2 teaspoons per 250 ml of boiling water. 

How To Take Kanna? 

From making tea to chewing it, Kanna has plenty of options. If you decide to take it as a tea, you’ll need to use about 200-500 mg when you brew it. Take it on an empty stomach. 

In order to sweeten it, you can add honey. Many state that if you decide to make a tea, it takes longer to kick in, but lasts longer. 

Kanna Effects

Kanna has psychoactive properties. One study believes that this is due to Sceletium alkaloids. These alkaloids are Membrenone and Mesembrine. Mesembrine is found to have strong serotonin-uptake inhibitory activity. 

Can Kanna Help With Anxiety? 

Many state that they take Kanna for a mood lift. Many state that it gives them a euphoric feeling. In order to achieve this feeling, it depends on the dose you take. 

Many claim that it produces an anxiolytic effect. This means it’s an anxiety mitigator. Some state that the alkaloid enriched S. tortuosum might benefit different forms of stress. 

This calming effect can be due to both the PDE4 inhibition and serotonin reuptake inhibition. Anxiety is often connected with chronic stress, and that’s why it’s believed to help. 


In the past, Kanna was fermented in order to make it easier to absorb and increase potentcy. It’s found that the fermentation process might break down oxalic acid which can be damaging in excess amounts. 

Kanna vs Kratom

Both are said to elevate your mood. Some believe that they contain anti-inflammatory and muscle relaxing alkaloids.

Some state that Kanna’s effects are more pronounced and are vision-inducing. Kratom doesn’t cause vision-inducing or intoxicating effects. 

Some strains of kratom are said to help you fall asleep at night. Many of those with sleep disorders enjoy taking kratom. 

Quick comparison: 

Kanna comes from a succulent plant. Kratom comes from the leaves of a tree. You can find that kratom is from Southeast Asia, and Kanna is from South Africa. 

How They Differ

Most of Kanna’s benefits are due to the Mesembrenone content. Whereas kratom’s are from its alkaloids. Mesembrenone is believed to be a serotonin reuptake inhibitor that causes anti-inflammation and enhanced cognition. 

While both of these herbs are used for recreational reasons, they have limited evidence. 

Kanna is said to primarily work on the amygdala. This is what’s responsible for relay and information processing. It’s supposed to make you feel more connected to nature and go into a meditative state. 

Kratom is said to have sedative effects at lower doses. Higher doses can cause a dream-like state. If you overdose on kratom, it can cause irritability and nausea. 

Comparing Kanna vs Kratom

After comparing Kanna vs kratom, you should have a better idea of which is right for you. Keep in mind that they alter different parts of your body and have different effects. 

Are you ready to start kratom or Kanna today? From Kanna powder to kratom capsules, you have options! Check out our various products on our site. 

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